The effect of quercetin combined with bornyl on anti-LPS-induced abortion was more significant, and the rate of CD4+/CD8+ was decreased to 0.562 + 0.021, lower than that of LPS-abortion group (P < 0.01). Antiinflammatory efficacies of monoterpenes remain still unknown. caused a reduction of 38.85%, 56.63% and 104.88%, respectively. An effort has been made to integrate chemistry and pharmacology while discussing the bioactive volatile constituents of essential oils. The modified CR showed higher antimicrobial activity in comparison to unmodified one. Monoterpenes act also as regulators of growth, heat, transpiration, tumor inhibitors, inhibitors of oxidative phosphorylation, insect repellants, feline and canine attractants and antidiabetics. The data demonstrate the pharmacological potential of this group of natural chemicals to act as anti-inflammatory drugs. Results: The average yield of oil was 0.46 ± 0.01% (v/w, dry leaves). Twenty-four components of P. atriplicifolia Benth. [19], Volatile monoterpenes produced by plants can attract or repel insects, thus some of them are used in insect repellents, such as citronellol, eucalyptol, limonene, linalool, hinokitiol, menthol and thymol. This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats. In separate experimental groups the response to 1,8-cineole (1-30 mg/kg), phenoterol (0.05-5 mg/kg) or vehicle (0.3% Tween in saline) was studied. Aujourd’hui, environ un français sur trois souffre de douleurs chroniques. reduced granuloma weight by 13.04% and 48.09%. Chestnut agrobiodiversity could be intended as strictly associated to the genotype effect and underlines the large variability within the genus Castanea, and therefore, the importance of in farm and ex situ conservation of local germplasm is part of a global strategy aimed at increasing the levels of agrobiodiversity. Oxygenated compounds were predominant (71.2%). inhibited the oedema by 46.90% and 67.83%, respectively. The essential oil of Ocimum basilicum was also analyzed by gas chromatography-mass spectrometry (GC/MS). [15][16], Many monoterpenes are used as food flavors and food additives, such as bornyl acetate, citral, eucalyptol, menthol, hinokitiol, camphene and limonene. 0 Le pulégone se présente alors comme une potentielle alternative au menthol dans différentes préparations pharmaceutiques permettant ainsi d’augmenter la dose de principe actif tout en diminuant les effets secondaires dû à la toxicité de celui-ci. A number of 45 constituents were identified by GC/MS. Conclusion: The increase of CD4+/CD8+ T cells in the LPS-treated mouse uterus could be associated with the embryo loss, and quercetin and bornyl acetate have an anti-abortive effect through modulation of maternal-fetal interface immune balance. Différentes techniques ont été optimisées pour l’extraction des terpènes volatils à partir de matière végétale à savoir l’hydrodistillation, l’extraction par liquide pressurisé (PLE), l’extraction dans l’espace de tête (HS), la microextraction sur phase solide dans l’espace de tête (HS-SPME), l’extraction par sorption dans l’espace de tête (HSSE) et enfin la microextraction liquide sur une goutte dans l’espace de tête couplée aux solvants eutectiques profonds (DES HS SDME). The oil of P. abrotanoides determined by a high content of monoterpens (61.85%) and it is a medicinal herb to treat leishmaniasisin. On the other hand, the maximal relaxant response to 1,8-cineole in carbachol-precontracted rat tracheas was 85.5 ± 5.7% (IC50 = 408.9 (328-5196) μg/ml) compared with 80.2 ± 4.8% (IC50 = 5.1 (4.3-6.1) μg/ml) with phenoterol. An investigation was undertaken to determine the 5-lipoxygenase inhibitory activity of aromatic plants traditionally used to treat dermatological pathologies. The aim of this study was to investigate the immune modulatory effect of orange juice and its components. them in special habitats. Monoterpenes and monoterpenoids are diverse. The study aimed at evaluating antibacterial and antifungal activity of EOs and composite resin material (CR) modified with EO against oral pathogens. Results: Thirty six compounds representing 98.1% of total oil were identified in the oil of Stachys athorecalyx. The test groups received Ocimum basilicum essential oil at doses of 100, 200, and 400 ml/kg two hours before induction of colitis. of Nigella sativa L. seeds and its active principle thymoquinone has been examined using carrageenan-induced oedema in rat hind paws and cotton seed pellet granuloma in rats. 153 0 obj <>/Filter/FlateDecode/ID[<0CAE6E2C07B5AF6AFB62B44B8B3785CE>]/Index[143 23]/Info 142 0 R/Length 72/Prev 264989/Root 144 0 R/Size 166/Type/XRef/W[1 3 1]>>stream In addition, most of the analysed chestnut cultivars showed a content of bioactive compounds similar to or higher than the main hazelnut, walnut, and almond varieties. The ease of peeling, seed colour, and intensity of sweetness were the sensory descriptors that allowed us to differentiate C. sativa cultivars. & Perovskia atriplicifolia... Chemical composition of the essential oils of Stachys athorecalyx C. Koch. The extracts did not exhibit antimicrobial action. Le but de cette thèse était d’explorer les propriétés anti-inflammatoires d’extraits de plantes thérapeutiques afin de les proposer comme traitement alternatif pour les douleurs chroniques inflammatoires. In the search for anti-inflammatory activity of monoterpenoids, inhibition of ovine cyclooxygenase-1 and -2 (COX-1 and COX-2) activity by 15 kinds of monoterpenoids (hydrocarbons, alcohols and ketones) with a p-menthane skeleton was investigated. p-C and RA (25-200 mg/kg) oral administration reduced the macroscopic lesion score, ulcerative area, intestinal weight/length ratio, and diarrheal index in TNBS-treated animals. This disorder reduces the quality of life and overall average productivity, causing huge financial losses. Furthermore, they modulated T cell populations (cluster of differentiation (CD)4 + , CD8 + , or CD3 + CD4 + CD25 +) analyzed from the spleen, mesenteric lymph nodes, and colon samples, and also decreased cyclooxigenase 2 (COX-2), interferon (IFN)-γ, inducible nitric oxide synthase (iNOS), and nuclear transcription factor kappa B subunit p65 (NFκB-p65) mRNA transcription, but only p-C interfered in the suppressor of cytokine signaling 3 (SOCS3) expression in inflamed colons. This is the first evidence of a steroid-like inhibition of arachidonic acid metabolism and IL-1β production by cineole. including anti-inflammatory activity. The oil of A. sessiflora displayed activity against the nitric oxide generation with the IC50 of 95.94 ± 6.18 µg/mL. Important terpenoids derived from monocyclic terpenes are menthol, thymol, hinokitiol, carvacrol, grapefruit mercaptan and many others.